Surprise twist: it's IV Abx.. Prophylactic Abx (often Ceftriaxone/PipTaz)➡️RR of 0.53 for rebleed (roughly the risk of rebleed is halved), with good effect upon mortality. TXA probably➡️no effect Cochrane 2010 https://t.co/THRSJDlMZK Good article from NNT
Surprise twist: it's IV Abx.. Prophylactic Abx (often Ceftriaxone/PipTaz)➡️RR of 0.53 for rebleed (roughly the risk of rebleed is halved), with good effect upon mortality. TXA probably➡️no effect Cochrane 2010 https://t.co/THRSJDlMZK Good article from NNT
Cochrane reviewをみると感染性疾患による死亡もちゃんと減ってるのよね。専門領域外なので解釈が難しいな・・・ ただ衛生が向上し抗菌薬の役割が小さく、薬価が安くなって供給が不安定なら使用しなくても・・・もありえる気がする(ガイドラインが推奨してるとやめにくいが) https://t.co/TjK09MCueX
@DrToddLee Cochran review claims 20% reduction in mortality which is difficult to believe. 12 studies of varying quality. Would have to check each individual one for actual rates. https://t.co/2QDFj6m5UR
@bonnefaux @ver_linkt Die Leitlinie empfiehlt es relativ explizit. https://t.co/pwNS3RItYY Unter Berufung auf u.a. diese Cochrane-Analyse. https://t.co/PyYIQoRGrk
@RealCedricDark for #8 and #9 I use ACEP policy for tpa and NINDS trial https://t.co/IAycRuIwmk and https://t.co/Qd3BuymXLw
The only drug with mortality benefit in a GI bleed....octreotide? Protonix? Nope! CEFTRIAXONE! https://t.co/FMhJx1mfcv #GIBleeds #Ceftriaxone
@mmc_im This meta-analysis reviewed 12 RCCs for the use of antibiotic prophylaxis in cirrhotic pts with upper GI bleeding. Reduces all cause mortality and hospitalization length. https://t.co/JReSBeCmHz
Remember to give antibiotics to cirrhotic pts presenting with an upper GI bleed https://t.co/9xtXw4dkZU #cincyai
RT @avkwong: Antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding - https://t.co/F31BsWs3cU #LIVES2016
RT @avkwong: Antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding - https://t.co/F31BsWs3cU #LIVES2016
Antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding - https://t.co/F31BsWs3cU #LIVES2016
Want to impact mortality for your cirrhotic w/ an upper GI bleed? Reach for the antibiotics http://t.co/FFM7a4LdtV #emconf #FOAMed
Want to impact mortality for your cirrhotic w/ an upper GI bleed? Reach for the antibiotics http://t.co/FFM7a4LdtV #emconf #FOAMed
Want to impact mortality for your cirrhotic w/ an upper GI bleed? Reach for the antibiotics http://t.co/FFM7a4LdtV #emconf #FOAMed
Want to impact mortality for your cirrhotic w/ an upper GI bleed? Reach for the antibiotics http://t.co/FFM7a4LdtV #emconf #FOAMed
La profilaxis antibiótica en HDA en pacientes cirróticos disminuye mortalidad, estancia media e infecciones. http://t.co/t8g6g6zvlI
Kissman: Antibiotics for patients w cirrhosis & upper GI bleed one of the few interventions that improves mortality: http://t.co/YhgY9tdkfX
Kissman: Antibiotics for patients w cirrhosis & upper GI bleed one of the few interventions that improves mortality: http://t.co/YhgY9tdkfX
@LWestafer you are probably aware of this review but here's a link for others http://t.co/g3ynioxv any comparison with other antibiotics?