Title |
Highâvolume haemofiltration for sepsis
|
---|---|
Published in |
Cochrane database of systematic reviews, January 2013
|
DOI | 10.1002/14651858.cd008075.pub2 |
Pubmed ID | |
Authors |
Borthwick EM, Hill CJ, Rabindranath KS, Maxwell AP, McAuley DF, Blackwood B, Borthwick, Emma MJ, Hill, Christopher J, Rabindranath, Kannaiyan S, Maxwell, Alexander P, McAuley, Danny F, Blackwood, Bronagh |
Abstract |
Severe sepsis and septic shock are leading causes of death in the intensive care unit (ICU). This is despite advances in the management of patients with severe sepsis and septic shock including early recognition, source control, timely and appropriate administration of antimicrobial agents, and goal directed haemodynamic, ventilatory and metabolic therapies. High-volume haemofiltration (HVHF) is a blood purification technique which may improve outcomes in critically ill patients with severe sepsis or septic shock. The technique of HVHF has evolved from renal replacement therapies used to treat acute kidney injury (AKI) in critically ill patients in the ICU. |
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