Title |
Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and psychological symptoms in older people with dementia
|
---|---|
Published in |
Cochrane database of systematic reviews, March 2013
|
DOI | 10.1002/14651858.cd007726.pub2 |
Pubmed ID | |
Authors |
Tom Declercq, Mirko Petrovic, Majda Azermai, Robert Vander Stichele, An IM De Sutter, Mieke L van Driel, Thierry Christiaens |
Abstract |
Antipsychotic agents are often used to treat neuropsychiatric symptoms (NPS) in dementia, although the literature is sceptical about their long-term use for this indication. Their effectiveness is limited and there is concern about adverse effects, including higher mortality with long-term use. When behavioural strategies have failed and drug therapy is instituted, regular attempts to withdraw these drugs are recommended. Physicians, nurses and families of older people with dementia are often reluctant to try to stop antipsychotics, fearing deterioration of NPS. Strategies to reduce antipsychotic use have been proposed, but a systematic review of interventions aimed at withdrawal of antipsychotic agents in older people with dementia has not yet been performed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 11 | 21% |
United Kingdom | 10 | 19% |
United States | 6 | 11% |
Canada | 4 | 8% |
France | 1 | 2% |
Chile | 1 | 2% |
Belgium | 1 | 2% |
Grenada | 1 | 2% |
Hungary | 1 | 2% |
Other | 2 | 4% |
Unknown | 15 | 28% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 39 | 74% |
Scientists | 7 | 13% |
Practitioners (doctors, other healthcare professionals) | 5 | 9% |
Science communicators (journalists, bloggers, editors) | 1 | 2% |
Unknown | 1 | 2% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 3 | <1% |
United Kingdom | 3 | <1% |
Chile | 1 | <1% |
Belgium | 1 | <1% |
Spain | 1 | <1% |
Unknown | 395 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 65 | 16% |
Researcher | 56 | 14% |
Student > Ph. D. Student | 42 | 10% |
Student > Bachelor | 42 | 10% |
Student > Doctoral Student | 31 | 8% |
Other | 97 | 24% |
Unknown | 71 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 168 | 42% |
Psychology | 37 | 9% |
Nursing and Health Professions | 28 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 28 | 7% |
Agricultural and Biological Sciences | 11 | 3% |
Other | 47 | 12% |
Unknown | 85 | 21% |