Benzos for back pain. Continually comes up clinically. Topic avoided in teaching and training. Therefore my practice differs from practising GPs. Evidence seems to be poor quality, but in favour of benzos. https://t.co/iTwtLXedWL
Nonbenzodiazepine muscle relaxants are more effective than placebo for short-term relief of acute low back pain (RR 0.80, 95% CI 0.71-0.89) with little difference between nonbenzodiazepine agents. https://t.co/4JCDjEiPjI
Interesting article "Muscle relaxants for non-specific low back pain" (via #pubmedontap) http://t.co/Xz8Tkinp7U
I was surprised by data on muscle relaxants for back pain. Decent treatment option per @CochraneCollab review: http://t.co/AHXRbwWAMN
@DoctorChristian rightly so. Good evidence for it http://t.co/3B5Xc1yDeH
@orthoandtrauma @intensegas @doctorchristian @maryportas & cochrane is explicit re diazepam not being obvious choice http://t.co/1NiDJIX3qj
@IntenseGas @doctorchristian @maryportas - precisely! As Cochrane says - http://t.co/1NiDJIX3qj
BZD系薬等の筋弛緩作用の腰痛に対するレビュー→http://t.co/Ba4RwxTwPd プラセボと比較して有意差あり。但し、中枢神経系の副作用の発現率を考慮する必要性があることやNSAIDsとの比較検討が必要とのこと。