| Title |
De‐escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock
|
|---|---|
| Published in |
Cochrane database of systematic reviews, March 2013
|
| DOI | 10.1002/14651858.cd007934.pub3 |
| Pubmed ID | |
| Authors |
Brenda NG Silva, Régis B Andriolo, Álvaro N Atallah, Reinaldo Salomão |
| Abstract |
Mortality rates among patients with sepsis, severe sepsis or septic shock are highly variable throughout different regions or services and can be upwards of 50%. Empirical broad-spectrum antimicrobial treatment is aimed at achieving adequate antimicrobial therapy, thus reducing mortality; however, there is a risk that empirical broad-spectrum antimicrobial treatment can expose patients to overuse of antimicrobials. De-escalation has been proposed as a strategy to replace empirical broad-spectrum antimicrobial treatment by using a narrower antimicrobial therapy. This is done by reviewing the patient's microbial culture results and then making changes to the pharmacological agent or discontinuing a pharmacological combination. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 29% |
| Japan | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 86% |
| Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 281 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| Germany | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 277 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 39 | 14% |
| Student > Master | 30 | 11% |
| Researcher | 26 | 9% |
| Student > Postgraduate | 24 | 9% |
| Other | 22 | 8% |
| Other | 72 | 26% |
| Unknown | 68 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 132 | 47% |
| Nursing and Health Professions | 18 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 15 | 5% |
| Biochemistry, Genetics and Molecular Biology | 9 | 3% |
| Agricultural and Biological Sciences | 6 | 2% |
| Other | 27 | 10% |
| Unknown | 74 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2016.
All research outputs
#3,079,514
of 25,806,763 outputs
Outputs from Cochrane database of systematic reviews
#5,753
of 13,140 outputs
Outputs of similar age
#24,663
of 211,323 outputs
Outputs of similar age from Cochrane database of systematic reviews
#91
of 212 outputs
Altmetric has tracked 25,806,763 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,140 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 35.9. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 211,323 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 212 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.