Title |
Brief co‐incubation of sperm and oocytes for in vitro fertilization techniques
|
---|---|
Published in |
Cochrane database of systematic reviews, April 2013
|
DOI | 10.1002/14651858.cd009391.pub2 |
Pubmed ID | |
Authors |
Zhongying Huang, Jun Li, Li Wang, Jing Yan, Yijiang Shi, Shangwei Li |
Abstract |
The in vitro fertilization (IVF) technique is commonly used and is the only treatment option for a proportion of infertile couples. To obtain better outcomes of IVF, it is important to enhance embryo quality by optimizing IVF techniques. In IVF procedures, oocytes and sperm are routinely co-incubated overnight, which may expose oocytes and zygotes to suboptimal culture conditions with increased reactive oxygen species (ROS) produced by sperm in this long term culture. As an attempt to avoid possible detrimental effects on the oocytes from long exposure to sperm, the brief co-incubation insemination protocol was developed. However, despite a number of studies in this area, it is unclear whether brief co-incubation improves the IVF outcomes compared with the standard overnight insemination protocol. |
X Demographics
Geographical breakdown
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United States | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
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Mendeley readers
Geographical breakdown
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Demographic breakdown
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