| Title |
Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder
|
|---|---|
| Published in |
Cochrane database of systematic reviews, October 2013
|
| DOI | 10.1002/14651858.cd003196.pub2 |
| Pubmed ID | |
| Authors |
Andrea Cipriani, Keith Reid, Allan H Young, Karine Macritchie, John Geddes |
| Abstract |
Bipolar disorder is a recurrent illness that is amongst the top 30 causes of disability worldwide and is associated with significant healthcare costs. In the past, emphasis was placed solely on the treatment of acute episodes of bipolar disorder; recently, the importance of episode prevention and of minimisation of iatrogenicity has been recognised. For many years, lithium was the only mood stabiliser in common use, and it remains an agent of first choice in the preventative treatment of bipolar disorder. However, an estimated 20% to 40% of patients may not respond adequately to lithium. Valproate is an anticonvulsant drug that has been shown to be effective in acute mania and is frequently used in maintenance treatment of bipolar disorder. When the acceptability of long-term treatment is considered, together with efficacy, the adverse event profile of a medication is also important. This is an update of a Cochrane review first published in 2001 and last updated in 2009. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 17% |
| Unknown | 5 | 83% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 518 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | <1% |
| Netherlands | 1 | <1% |
| Australia | 1 | <1% |
| United Kingdom | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 511 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 67 | 13% |
| Researcher | 60 | 12% |
| Student > Master | 58 | 11% |
| Student > Postgraduate | 36 | 7% |
| Student > Ph. D. Student | 35 | 7% |
| Other | 112 | 22% |
| Unknown | 150 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 154 | 30% |
| Psychology | 40 | 8% |
| Nursing and Health Professions | 32 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 29 | 6% |
| Biochemistry, Genetics and Molecular Biology | 20 | 4% |
| Other | 76 | 15% |
| Unknown | 167 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 30. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 September 2022.
All research outputs
#1,318,145
of 25,457,858 outputs
Outputs from Cochrane database of systematic reviews
#2,791
of 11,842 outputs
Outputs of similar age
#11,939
of 224,748 outputs
Outputs of similar age from Cochrane database of systematic reviews
#48
of 209 outputs
Altmetric has tracked 25,457,858 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,842 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.9. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 224,748 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 209 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.