@GillianKolla RCTs, meta analyses and Systematic reviews all in favour of prescription opioids. "Methadone is superior to buprenorphine in retaining people in treatment" Hard to beat Cochrane review. https://t.co/P1SN1qqoWx
@0xpanoprx @DavidJuurlink Comorbid chronic pain/illness More dose range availability Some people just respond better to methadone How many reasons do want https://t.co/TTzWJZK1r2 Why not let the patient decide what’s best for them after explaining benef
@MaxJordan_N @LeoBeletsky Sure, it's possible that high dose bupe would work just as well, but if we're going to advocate for evidence-based medicine, we should stick to the best evidence we have: https://t.co/WzkXvUYMRN
@_Eric_Reinhart @MaxJordan_N @LeoBeletsky I haven’t dug into these (& not sure about power for these outcomes), but that’s the conclusion of 2014 Cochrane review of RCTs https://t.co/RXTzbXz7rB https://t.co/fqmMJddS79
Tässä siis toi tutkimus https://t.co/KvwAO6vrlm
RT @ErikaKeskiK: Ilman tutkimustakin olisi voitu todeta järjestäytyneen huumekauppaverkoston sitovan taloudellisia riippuvuussuhteita narko…
Ilman tutkimustakin olisi voitu todeta järjestäytyneen huumekauppaverkoston sitovan taloudellisia riippuvuussuhteita narkomaaneihin paremmin opioideilla kuin placepolla. Narkomaani pysyy hyödykkeenä paremmin kun antaa placebon sijaan opioideja. https://t.c
Same with Suboxone (generic name: buprenorphine). Numerous studies have shown it is just as good as methadone (if not better) at treating OUD and preventing relapse. 12/ https://t.co/pTvPcbEq15
RT @adfoxMD: Also, creating hierarchy where buprenorphine good and methadone bad will inherently lead to more overdose deaths Methadone b…
RT @adfoxMD: Also, creating hierarchy where buprenorphine good and methadone bad will inherently lead to more overdose deaths Methadone b…
Louder for folks in the back. And read @adfoxMD’s whole thoughtful 🧵
Also, creating hierarchy where buprenorphine good and methadone bad will inherently lead to more overdose deaths Methadone better retains ppl in care when doses are titrated to patient's need based on opioid craving https://t.co/7lU9gBI2DE Bupe isn't f
RT @ADrugResearcher: @TahirTturk @wait_what_wait @MauriceGSwanson @tobaccofreeaust @AlexWodak Suboxone vs methadone (methadone appears bett…
@TahirTturk @wait_what_wait @MauriceGSwanson @tobaccofreeaust @AlexWodak Suboxone vs methadone (methadone appears better, but suboxone still works - people need options) Cochrane review: https://t.co/kQWAYYQNNI
Tvärtom mot vad Bejerot säger så visar studier av substitutbehandling gång på gång att dödligheten minskar med programmen. Studier finns bland annat att läsa här: https://t.co/vogdm74DRd https://t.co/tEJbiWGoQv
RT @TheNewImpostor: what matters isn't what people prefer to think, but what systematic & comprehensive reviews of the evidence show https:…
what matters isn't what people prefer to think, but what systematic & comprehensive reviews of the evidence show https://t.co/Ka147RxxBR https://t.co/ZZyk2qFZqC https://t.co/NbE4vyOzT3 https://t.co/LyMAeY8KhK https://t.co/pVk4F9Ebon https://t.co/0RGOW3
@TheKanehB what matters isn't what people prefer to think, but what systematic & comprehensive reviews of the evidence show https://t.co/Ka147RxxBR https://t.co/ZZyk2qFZqC https://t.co/NbE4vyOzT3 https://t.co/LyMAeY8KhK https://t.co/pVk4F9Ebon https://
OJPNIJ: This rating is based on a review of the meta-analysis “Buprenorphine Maintenance Versus Placebo or Methadone Maintenance for Opioid Dependence.” Review the study: https://t.co/V3T9jltyoi
RT @OJPNIJ: This rating is based on a review of the meta-analysis “Buprenorphine Maintenance Versus Placebo or Methadone Maintenance for Op…
This rating is based on a review of the meta-analysis “Buprenorphine Maintenance Versus Placebo or Methadone Maintenance for Opioid Dependence.” Review the study: https://t.co/Gp3Tmn9QrP
1 in 2 patients on buprenorphine (≥16mg) had retention in treatment. NNT=2 https://t.co/xYRRqpnYBy
@DrJSPotter @HillPharmD @JonGiftosMD @StefanKertesz @jefbratberg @JessLynnMoreno @ACLakeMD @DrSarahWakeman @ml_barnett I’ve always scratched my head at the reluctance to rx 16mg of bup or higher, esp since that’s the baseline dose with the most efficacy (👇
RT @tdbrothers: But even for people with access to OAT, not all OAT is equal Meta-analyses of multiple RCTs established minimum effective…
RT @tdbrothers: But even for people with access to OAT, not all OAT is equal Meta-analyses of multiple RCTs established minimum effective…
RT @tdbrothers: But even for people with access to OAT, not all OAT is equal Meta-analyses of multiple RCTs established minimum effective…
But even for people with access to OAT, not all OAT is equal Meta-analyses of multiple RCTs established minimum effective doses for methadone (60mg or higher) https://t.co/3miZr6EJkx and buprenorphine (16mg or higher) https://t.co/ZN5BebcvJu
RT @DavidSFink: @Village4Addicts @PatrickDoyle_35 Here are several on MAT in general, all show evidence for MAT, which is unequivocally sup…
Yup! Thanks @DavidSFink
8. Goal should be to reach a dose that blocks craving. @liebschutz et al reached 16 mg by day 3. 16 mg more effective than lower dose - often “lower better” mentality driven by stigma https://t.co/wYeN8Uuhe7 https://t.co/q0p5PEyWKk
@AddictionDocOH Methadone maintenance has been studied for 50 yrs w/ strong evidence of safety & efficacy. I believe these studies, you can make your clinical decisions however you wish to: https://t.co/8ZrudKE8JT https://t.co/HTyVHBUg4k https://t.co/7
RT @DrSarahWakeman: @aribindi @KeithAhamad @Atul_Gawande @ml_barnett @NEJM Rigorous research always needed; but already exists for meds for…
RT @DrSarahWakeman: @aribindi @KeithAhamad @Atul_Gawande @ml_barnett @NEJM Rigorous research always needed; but already exists for meds for…
RT @DrSarahWakeman: @aribindi @KeithAhamad @Atul_Gawande @ml_barnett @NEJM Rigorous research always needed; but already exists for meds for…
RT @DrSarahWakeman: @aribindi @KeithAhamad @Atul_Gawande @ml_barnett @NEJM Rigorous research always needed; but already exists for meds for…
RT @DrSarahWakeman: @aribindi @KeithAhamad @Atul_Gawande @ml_barnett @NEJM Rigorous research always needed; but already exists for meds for…
RT @CarlynZwaren: This is an important distinction to be aware of. https://t.co/CLxuUgeLRU
RT @DrSarahWakeman: @aribindi @KeithAhamad @Atul_Gawande @ml_barnett @NEJM Rigorous research always needed; but already exists for meds for…
This is an important distinction to be aware of. https://t.co/CLxuUgeLRU
RT @LizSamuels: @JoshuaNiforatos @dhdqhllc @meganranney @TheSGEM @SAEMEBM @DrSarahWakeman That's exactly what we are talking about! And yes…
@JoshuaNiforatos @dhdqhllc @meganranney @TheSGEM @SAEMEBM @DrSarahWakeman That's exactly what we are talking about! And yes, buprenorphine/suboxone is evidence based treatment for opioid use disorder. https://t.co/oMFYNKBkDS
@DrSarahWakeman @hakique @DocVan_Nostrand @StefanKertesz The Cochrane review on buprenorphine notes that most RCTs report zero deaths in either intervention or control groups -- possibly due to short duration of follow-up https://t.co/el7SXi5RLC 4/n htt
@DrSarahWakeman @hakique @DocVan_Nostrand @StefanKertesz But RCTs & Cochrane meta-analysis show no mortality benefit for either: https://t.co/el7SXi5RLC https://t.co/2Xjb8oRlNi 3/n https://t.co/MNUYC86zxt
“buprenorphine did not suppress illicit opioid use measured by urinanalysis better than placebo” https://t.co/rx9DBnDXDd
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
To repeat: medication helps to reduce abuse and keep people in treatment. And #naltrexone, excellent for #opioids, also works for #alcohol. https://t.co/8fgTtDzr22
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
RT @asacarny: systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/…
systematic reviews: medication helps to reduce abuse and keep people in treatment 1. https://t.co/vM6DOOlGF0 2. https://t.co/Dk0an50GMd https://t.co/koURZ33Qhq
Wondered about #buprenorphine vs. #methadone & other #MAT txs? Here's some research for quench your inquiry. https://t.co/7dQ4IswH8k
@Noahpinion suboxone reduces illicit use and mortality https://t.co/bsAbiP1WHx
RT @Mavriks_Island: @drdrew https://t.co/XNkSziZeOB This proposes that bupe treatment has even/lower retention rates then methadone dependi…
@drdrew https://t.co/XNkSziZeOB This proposes that bupe treatment has even/lower retention rates then methadone depending on dose. Thoughts?
buprenorfina versus placebo o mantenimiento con metadona para la dependencia de opiáceos Resúmenes Cochrane - http://t.co/hoLNObXUwD
buprenorfina versus placebo o mantenimiento con metadona para la dependencia de opiáceos Resúmenes Cochrane - http://t.co/hoLNObXUwD
buprenorfina versus placebo o mantenimiento con metadona para la dependencia de opiáceos Resúmenes Cochrane - http://t.co/pq0AdkdE7K
buprenorfina versus placebo o mantenimiento con metadona para la dependencia de opiáceos Resúmenes Cochrane - http://t.co/pq0AdkdE7K
Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence http://t.co/EQ0mFHz4Xm
Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence #Cochrane Mattick http://t.co/26S67wexNk
How does buprenorphine compare to placebo or #methadone for reducing #opioid dependence? | Updated #Cochrane Review | http://t.co/e4JdaISVv1
How does buprenorphine maintenance compare to placebo and to methadone in the management of opioid dependence? http://t.co/nENVCra8Lm
@CochraneLibrary: Buprenorphine less effective than methadone for opioid dependence, in a flexible dose regimen... http://t.co/xOsC1ay2CU
How does buprenorphine maintenance compare to placebo and to methadone in the management of opioid dependence? http://t.co/nENVCra8Lm