Title |
Pharmacological treatment of children with gastro‐oesophageal reflux
|
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Published in |
Cochrane database of systematic reviews, November 2014
|
DOI | 10.1002/14651858.cd008550.pub2 |
Pubmed ID | |
Authors |
Mark Tighe, Nadeem A Afzal, Amanda Bevan, Andrew Hayen, Alasdair Munro, R Mark Beattie |
Abstract |
Gastro-oesophageal reflux (GOR) is a common disorder, characterised by regurgitation of gastric contents into the oesophagus. GOR is a very common presentation in infancy in both primary and secondary care settings. GOR can affect approximately 50% of infants younger than three months old (Nelson 1997). The natural history of GOR in infancy is generally that of a functional, self-limiting condition that improves with age; < 5% of children with vomiting or regurgitation continue to have symptoms after infancy (Martin 2002). Older children and children with co-existing medical conditions can have a more protracted course. The definition of gastro-oesophageal reflux disease (GORD) and its precise distinction from GOR are debated, but consensus guidelines from the North American Society of Gastroenterology, Hepatology and Nutrition (NASPGHAN-ESPGHAN guidelines 2009) define GORD as 'troublesome symptoms or complications of GOR.' OBJECTIVES: This Cochrane review aims to provide a robust analysis of currently available pharmacological interventions used to treat children with GOR by assessing all outcomes indicating benefit or harm. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 4 | 17% |
Spain | 3 | 13% |
Canada | 2 | 8% |
United States | 1 | 4% |
Argentina | 1 | 4% |
Unknown | 13 | 54% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 22 | 92% |
Practitioners (doctors, other healthcare professionals) | 2 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 1 | <1% |
Chile | 1 | <1% |
Korea, Republic of | 1 | <1% |
Brazil | 1 | <1% |
United Kingdom | 1 | <1% |
Canada | 1 | <1% |
Unknown | 408 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 64 | 15% |
Student > Bachelor | 51 | 12% |
Researcher | 43 | 10% |
Student > Ph. D. Student | 33 | 8% |
Other | 29 | 7% |
Other | 83 | 20% |
Unknown | 111 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 139 | 34% |
Nursing and Health Professions | 53 | 13% |
Psychology | 19 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 18 | 4% |
Social Sciences | 15 | 4% |
Other | 35 | 8% |
Unknown | 135 | 33% |