Long‐acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults with asthma

Overview of attention for article published in Cochrane database of systematic reviews, July 2015

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In the top 25% of all research outputs scored by Altmetric
High Attention Score compared to outputs of the same age (93rd percentile)
Good Attention Score compared to outputs of the same age and source (75th percentile)

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Je li bolje ljudima s nekontroliranom astmom koji koriste inhalirane kortikosteroide povisiti dozu kortikosteroida ili dodati…

For people with uncontrolled asthma on inhaled steroids, is it better to increase the dose or add a long-acting muscarinic…

SAEs &hospitalisations occurred in similarly low numbers of pts on each treatment; CIs too wide to prove equivalence http://ow.ly…

...but the confidence intervals for both outcomes didn't exclude possibility that double dose ICS was more effective http://ow.ly…

Fewer people on tio had an exacerbation req OCS (OR 0.57,95% CI 0.22-1.43) or ED visit (OR 0.49, 95% CI 0.09-2.77)... http://ow.l…

Review included 1 crossover RCT on 210 people w/mod-severe asthma. Compared tiotropium w/double dose beclomethasone http://ow.ly…

New #Cochrane review: Long-acting muscarinic antagonists (LAMA) added to ICS vs higher dose ICS for adults w/asthma http://ow.ly…