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Cochrane Database of Systematic Reviews

Treatment for chronic methicillin-sensitiveStaphylococcus aureuspulmonary infection in people with cystic fibrosis

Overview of attention for article published in Cochrane database of systematic reviews, March 2016
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  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Average Attention Score compared to outputs of the same age and source

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7 X users
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Citations

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31 Mendeley
Title
Treatment for chronic methicillin-sensitiveStaphylococcus aureuspulmonary infection in people with cystic fibrosis
Published in
Cochrane database of systematic reviews, March 2016
DOI 10.1002/14651858.cd011581.pub2
Pubmed ID
Authors

Molla I Ahmed, Saptarshi Mukherjee

Abstract

Cystic fibrosis is an inherited life-threatening multisystem disorder with lung disease characterized by abnormally thick airway secretions and persistent bacterial infection. Chronic, progressive lung disease is the most important cause of morbidity and mortality in the condition and is therefore the main focus of clinical care and research. Staphylococcus aureus is a major cause of chest infection in people with cystic fibrosis. Early onset, as well as chronic, lung infection with this organism in young children and adults results in worsening lung function, poorer nutrition and increases the airway inflammatory response, thus leading to a poor overall clinical outcome. There are currently no evidence-based guidelines for chronic suppressive therapy for Staphylococcus aureus infection in cystic fibrosis such as those used for Pseudomonas aeruginosa infection. To assess the evidence regarding the effectiveness of long-term antibiotic treatment regimens for chronic infection with methicillin-sensitive Staphylococcus aureus (MSSA) infection in people with cystic fibrosis and to determine whether this leads to improved clinical and microbiological outcomes. Trials were identified by searching the Cochrane Cystic Fibrosis and Genetic Disorders Group's Cystic Fibrosis Trials Register, MEDLINE, Embase, handsearching article reference lists and through contact with local and international experts in the field. We also searched ongoing trials databases.Date of the last search of the Group's Cystic Fibrosis Trials Register: 03 March 2016. Randomised or quasi-randomised controlled trials comparing any combinations of topical, inhaled, oral or intravenous antimicrobials used as suppressive therapy for chronic infection with methicillin-sensitive Staphylococcus aureus compared with placebo or no treatment. The authors independently assessed all search results for eligibility. No eligible trials were identified. The searches identified 55 trials, but none were eligible for inclusion in the current version of this review. No randomised controlled trials were identified which met the inclusion criteria for this review. Although methicillin-sensitive Staphylococcus aureus is an important and common cause of lung infection in people with cystic fibrosis, there is no agreement on how best to treat long-term infection. The review highlights the need to organise well-designed trials that can provide evidence to support the best management strategy for chronic methicillin-sensitive Staphylococcus aureus infection in people with cystic fibrosis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 16%
Researcher 4 13%
Student > Master 4 13%
Student > Ph. D. Student 3 10%
Student > Postgraduate 2 6%
Other 6 19%
Unknown 7 23%
Readers by discipline Count As %
Medicine and Dentistry 11 35%
Immunology and Microbiology 7 23%
Agricultural and Biological Sciences 2 6%
Biochemistry, Genetics and Molecular Biology 1 3%
Business, Management and Accounting 1 3%
Other 4 13%
Unknown 5 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 May 2016.
All research outputs
#5,982,523
of 22,856,968 outputs
Outputs from Cochrane database of systematic reviews
#7,781
of 12,325 outputs
Outputs of similar age
#84,675
of 300,114 outputs
Outputs of similar age from Cochrane database of systematic reviews
#193
of 282 outputs
Altmetric has tracked 22,856,968 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 12,325 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.5. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,114 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 282 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.