↓ Skip to main content

Cochrane Database of Systematic Reviews

Gastro-oesophageal reflux treatment for asthma in adults and children

Overview of attention for article published in Cochrane database of systematic reviews, January 2003
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

news
1 news outlet

Citations

dimensions_citation
199 Dimensions

Readers on

mendeley
77 Mendeley
citeulike
1 CiteULike
Title
Gastro-oesophageal reflux treatment for asthma in adults and children
Published in
Cochrane database of systematic reviews, January 2003
DOI 10.1002/14651858.cd001496
Pubmed ID
Authors

Peter G Gibson, Richard Henry, Jennifer JL Coughlan

Abstract

Asthma and gastro-oesophageal reflux are both common medical conditions and often co-exist. Studies have shown conflicting results concerning the effects of lower oesophageal acidification as a trigger of asthma. Furthermore, asthma might precipitate gastro-oesophageal reflux. Thus a temporal association between the two does not establish that gastro-oesophageal reflux triggers asthma. Randomised trials of a number of treatments for gastro-oesophageal reflux in asthma have been conducted to determine whether treatment of reflux improves asthma. The objective of this review was to evaluate the effectiveness of treatments for gastro-oesophageal reflux in terms of their benefit on asthma. The Cochrane Airways Group trials register, review articles and reference lists of articles were searched. Randomised controlled trials of treatment for oesophageal reflux in adults and children with a diagnosis of both asthma and gastro-oesophageal reflux. Trial quality and data extraction were carried out by two independent reviewers. Authors were contacted for confirmation or more data. Twelve trials met the inclusion criteria. Interventions included proton pump inhibitors (n=6), histamine antagonists (n=5), surgery (n=1) and conservative management (n=1). Treatment duration ranged from 1 week to 6 months. A temporal association between asthma and gastro-oesophageal reflux was investigated in 4 trials and found to be present in a proportion of participants in these trials. Anti-reflux treatment did not consistently improve lung function, asthma symptoms, nocturnal asthma or the use of asthma medications. In asthmatic subjects with gastro-oesophageal reflux, (but who were not recruited specifically on the basis of reflux-associated respiratory symptoms), there was no overall improvement in asthma following treatment for gastro-oesophageal reflux. Subgroups of patients may gain benefit, but it appears difficult to predict responders.

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Japan 1 1%
United States 1 1%
Germany 1 1%
Unknown 73 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 13%
Researcher 10 13%
Student > Master 9 12%
Professor > Associate Professor 6 8%
Student > Doctoral Student 6 8%
Other 24 31%
Unknown 12 16%
Readers by discipline Count As %
Medicine and Dentistry 45 58%
Pharmacology, Toxicology and Pharmaceutical Science 4 5%
Nursing and Health Professions 4 5%
Biochemistry, Genetics and Molecular Biology 2 3%
Immunology and Microbiology 1 1%
Other 4 5%
Unknown 17 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 October 2017.
All research outputs
#3,177,127
of 12,527,093 outputs
Outputs from Cochrane database of systematic reviews
#5,310
of 8,923 outputs
Outputs of similar age
#74,440
of 262,978 outputs
Outputs of similar age from Cochrane database of systematic reviews
#98
of 156 outputs
Altmetric has tracked 12,527,093 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 8,923 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 21.2. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,978 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 156 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.