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Cochrane Database of Systematic Reviews

Short versus standard duration oral antibiotic therapy for acute urinary tract infection in children

Overview of attention for article published in Cochrane database of systematic reviews, January 2003
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

Mentioned by

blogs
2 blogs
policy
2 policy sources

Citations

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85 Dimensions

Readers on

mendeley
96 Mendeley
Title
Short versus standard duration oral antibiotic therapy for acute urinary tract infection in children
Published in
Cochrane database of systematic reviews, January 2003
DOI 10.1002/14651858.cd003966
Pubmed ID
Authors

Mini Michael, Elisabeth M Hodson, Jonathan C Craig, Sarah Martin, Virginia A Moyer

Abstract

The optimal duration of oral antibiotic therapy for urinary tract infection (UTI) in children has not been determined. A number of studies have compared single dose therapy to standard therapy for UTI, with mixed results. A course of antibiotics longer than a single dose but shorter than the usual 7-10 days might decrease the relapse rate and still provide some of the benefits of a shortened course of antibiotics. The objective of this review was to assess the benefits and harms of short-course (2-4 days) compared to standard duration (7-14 days) oral antibiotic treatment for acute UTI in children. We searched the Cochrane Controlled Trials Register (Cochrane Library Issue 3, 2002) MEDLINE (1966 - September 2002) and EMBASE (1988 -September 2002) without language restriction. Randomised and quasi-randomised controlled trials comparing short-term (2-4 days) with standard (7-14 days) oral antibiotic therapy were selected if they studied children aged three months to 18 years with culture proven UTI. Two reviewers independently assessed trial quality and extracted data. Statistical analyses were performed using the random effects model and the results expressed as relative risk (RR) with 95% confidence intervals (95% CI). Ten trials were identified in which 652 children with lower tract UTI were evaluated. There was no significant difference in the frequency of positive urine cultures between the short (2-4 days) and standard duration oral antibiotic therapy (7-14 days) for UTI in children at 0-10 days after treatment (eight studies: RR 1.06; 95% CI 0.64 to 1.76) and at one to 15 months after treatment (10 studies: RR 0.95; 95% CI 0.70 to 1.29). There was no significant difference between short and standard duration therapy in the development of resistant organisms in UTI at the end of treatment (one study: RR 0.57, 95% CI 0.32 to 1.01) or in recurrent UTI (three studies: RR 0.39, 95% CI 0.12 to 1.29). A 2-4 day course of oral antibiotics appears to be as effective as 7-14 days in eradicating lower tract UTI in children.

Mendeley readers

The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 1%
United States 1 1%
Germany 1 1%
Belgium 1 1%
Unknown 92 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 17 18%
Student > Master 15 16%
Researcher 14 15%
Other 8 8%
Student > Postgraduate 7 7%
Other 18 19%
Unknown 17 18%
Readers by discipline Count As %
Medicine and Dentistry 47 49%
Nursing and Health Professions 8 8%
Pharmacology, Toxicology and Pharmaceutical Science 8 8%
Biochemistry, Genetics and Molecular Biology 3 3%
Computer Science 2 2%
Other 7 7%
Unknown 21 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2018.
All research outputs
#1,383,201
of 17,363,630 outputs
Outputs from Cochrane database of systematic reviews
#3,521
of 11,660 outputs
Outputs of similar age
#39,122
of 366,093 outputs
Outputs of similar age from Cochrane database of systematic reviews
#79
of 207 outputs
Altmetric has tracked 17,363,630 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,660 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.0. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 366,093 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 207 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.