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Cochrane Database of Systematic Reviews

Extubation from low-rate intermittent positive airway pressure versus extubation after a trial of endotracheal continuous positive airway pressure in intubated preterm infants

Overview of attention for article published in Cochrane database of systematic reviews, October 2001
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Title
Extubation from low-rate intermittent positive airway pressure versus extubation after a trial of endotracheal continuous positive airway pressure in intubated preterm infants
Published in
Cochrane database of systematic reviews, October 2001
DOI 10.1002/14651858.cd001078
Pubmed ID
Authors

Peter G Davis, David J Henderson-Smart

Abstract

Failure of extubation and subsequent reintubation may result in additional stress and trauma to the premature infant. Testing infants about to be extubated with a period of endotracheal CPAP has been suggested as a method of demonstrating readiness for extubation. However, this process has been criticized as increasing the neonate's work of breathing and perhaps increasing the likelihood of extubation failure. In premature infants having their endotracheal tube removed, is direct extubation from low rate intermittent positive pressure ventilation (IPPV) more successful than that following a period of endotracheal continuous positive airway pressure (CPAP)? The standard search strategy of the Neonatal Review Group as outlined in the Cochrane Library was used. This included searches of the Oxford Database of Perinatal Trials, Cochrane Controlled Trials Register, MEDLINE, previous reviews including cross references, abstracts, conferences, symposia proceedings, expert informants and journal hand searching mainly in the English language. All trials using random or quasi-random allocation of premature infants to endotracheal CPAP or direct extubation following a period of IPPV were included. Data were extracted using standard methods of the Cochrane Collaboration and its Neonatal Review Group, with separate evaluation of trial quality and data extraction by each author and synthesis of data using relative risk. Direct extubation from low rate ventilation is associated with a trend to increased chance of successful extubation when compared to extubation after a period of endotracheal CPAP, RR 0.45 (0.19,1.07), RD -0.103 (-0.200,-0.006), NNT 10 (5,167). When only truly randomized trials are considered, this result becomes both statistically significant and clinically important, RR 0.10 (0.01,0.78), RD -0.201 (-0.319,-0.083), NNT 5 (3,12). Similar differences are seen for the secondary outcome, apnea. Preterm infants no longer requiring endotracheal intubation and IPPV should be directly extubated without a trial of ETT CPAP.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 <1%
Unknown 114 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 16 14%
Student > Master 13 11%
Student > Postgraduate 12 10%
Researcher 11 10%
Other 7 6%
Other 20 17%
Unknown 36 31%
Readers by discipline Count As %
Medicine and Dentistry 49 43%
Nursing and Health Professions 12 10%
Psychology 6 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Agricultural and Biological Sciences 2 2%
Other 6 5%
Unknown 38 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 December 2020.
All research outputs
#15,443,875
of 22,953,506 outputs
Outputs from Cochrane database of systematic reviews
#10,813
of 12,333 outputs
Outputs of similar age
#39,982
of 44,019 outputs
Outputs of similar age from Cochrane database of systematic reviews
#22
of 23 outputs
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We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.