Title |
Anticoagulation therapy versus placebo for pulmonary hypertension
|
---|---|
Published in |
Cochrane database of systematic reviews, June 2014
|
DOI | 10.1002/14651858.cd010695.pub2 |
Pubmed ID | |
Authors |
Ifeanyi R Ezedunukwe, Hilary Enuh, Jay Nfonoyim, Collins U Enuh |
Abstract |
Elevation of pulmonary pressure is no longer a rare disease, given its multifactorial etiology. However data on the actual incidence of this condition are still limited, and controversies regarding its management are ongoing. Use of anticoagulation in the management of pulmonary hypertension is based on the presence of in situ thrombosis in the patient with pulmonary arterial hypertension (PAH) and on retrospective evidence of clinical benefit. Current practice is dependent mostly on expert opinion and individualised experience. The real benefit of its use in different types of pulmonary hypertension is still debatable, and the therapeutic target of the international normalised ratio (INR) among treated patients remains inconclusive. Adverse outcomes associated with anticoagulants are significant and can include fatal haemorrhage. Justification for the use of this intervention requires critical evaluation of randomised controlled trials. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 20% |
Unknown | 4 | 80% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 60% |
Scientists | 1 | 20% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | <1% |
France | 1 | <1% |
Unknown | 177 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 23 | 13% |
Student > Ph. D. Student | 16 | 9% |
Student > Bachelor | 16 | 9% |
Researcher | 14 | 8% |
Student > Postgraduate | 12 | 7% |
Other | 37 | 21% |
Unknown | 61 | 34% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 59 | 33% |
Nursing and Health Professions | 16 | 9% |
Social Sciences | 8 | 4% |
Psychology | 5 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 3% |
Other | 17 | 9% |
Unknown | 69 | 39% |