Title |
Surgical treatment of stage IA2 cervical cancer
|
---|---|
Published in |
Cochrane database of systematic reviews, May 2014
|
DOI | 10.1002/14651858.cd010870.pub2 |
Pubmed ID | |
Authors |
Fani Kokka, Andrew Bryant, Elly Brockbank, Arjun Jeyarajah |
Abstract |
Cervical cancer is the second most common cancer among women up to 65 years of age and is the most frequent cause of death from gynaecological cancers worldwide. Women with International Federation of Gynecology and Obstetrics (FIGO) stage IA2 cervical cancer have measured stromal invasion (when the cancer breaks through the basement membrane of the epithelium) of greater than 3 mm and no greater than 5 mm in depth with a horizontal surface extension of no more than 7 mm. For stage IA2 disease, radical hysterectomy with pelvic lymphadenectomy or radiotherapy is the standard treatment. In order to avoid complications of more radical surgical methods, less invasive options, such as simple hysterectomy, simple trachelectomy or conisation, with or without pelvic lymphadenectomy, may be feasible for stage IA2 disease, considering the relative low risk of local or distant metastatic disease. The evidence for less radical tumour excision and for the role of systematic lymphadenectomy in stage IA2 cervical cancer is not clear. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 174 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 23 | 13% |
Student > Bachelor | 19 | 11% |
Unspecified | 17 | 10% |
Researcher | 13 | 7% |
Student > Postgraduate | 12 | 7% |
Other | 36 | 21% |
Unknown | 54 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 61 | 35% |
Nursing and Health Professions | 20 | 11% |
Unspecified | 17 | 10% |
Biochemistry, Genetics and Molecular Biology | 4 | 2% |
Social Sciences | 4 | 2% |
Other | 9 | 5% |
Unknown | 59 | 34% |