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Cochrane Database of Systematic Reviews

Antibiotics for asymptomatic bacteriuria

Overview of attention for article published in Cochrane database of systematic reviews, April 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

1 blog
1 policy source
55 X users
8 Facebook pages
3 Wikipedia pages
1 Google+ user


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290 Mendeley
Antibiotics for asymptomatic bacteriuria
Published in
Cochrane database of systematic reviews, April 2015
DOI 10.1002/14651858.cd009534.pub2
Pubmed ID

Anca Zalmanovici Trestioreanu, Adi Lador, May‐Tal Sauerbrun‐Cutler, Leonard Leibovici


Asymptomatic bacteriuria is commonly detected in women aged up to 60 years, patients with diabetes, and the elderly. The benefit of antibiotic treatment for this condition is controversial. To assess the effectiveness and safety of antibiotics treatment for asymptomatic bacteriuria in adults. Specific objectives were to assess 1) the effectiveness of antibiotics for preventing development of symptomatic UTI, UTI-related complications, overall mortality, UTI-related mortality, and resolution of bacteriuria; 2) the development of resistance to antibiotic treatment by comparing resistance of grown bacteria in urine before and after therapy; and 3) the frequency of adverse events. We searched the Cochrane Renal Group's Specialised Register up to 24 February 2015 through contact with the Trials' Search Co-ordinator using search terms relevant to this review. Randomised controlled trials (RCTs) and quasi-RCTs comparing antibiotics to placebo or no treatment for asymptomatic bacteriuria in adults were included. The outcomes of interest were the development of symptomatic urinary tract infection (UTI), complications, death, any adverse event, development of antibiotic resistance, bacteriological cure, and decline in kidney function. Two authors independently extracted the data and assessed study quality. Statistical analyses were performed using the random effects model and the results expressed as risk ratios (RR) with 95% confidence intervals (CI). We included nine studies (1614 participants) in this review. Symptomatic UTI (RR 1.11, 95% CI 0.51 to 2.43), complications (RR 0.78, 95% CI 0. 35 to 1.74), and death (RR 0.99, 95% CI 0.70 to 1.41) were similar between the antibiotic and placebo or no treatment arms. Antibiotics were more effective for bacteriological cure (RR 2.32, 95% CI 1.11 to 4.83) but also more adverse events developed in this group (RR 3.77, 95% CI 1.40 to 10.15). No decline in the kidney function was observed across the studies; minimal data were available on the emergence of resistant strains after antimicrobial treatment.The included studies were of medium and high quality, used different treatments for different durations of treatment and follow-up, different populations, but this did not appear to influence the results of review. No differences were observed between antibiotics versus no treatment of asymptomatic bacteriuria for the development of symptomatic UTI, complications or death. Antibiotics were superior to no treatment for the bacteriological cure but with significantly more adverse events. There was no clinical benefit from treating asymptomatic bacteriuria in the studies included in this review.

X Demographics

X Demographics

The data shown below were collected from the profiles of 55 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 290 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Colombia 1 <1%
United States 1 <1%
Unknown 287 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 47 16%
Student > Bachelor 41 14%
Researcher 25 9%
Other 23 8%
Student > Postgraduate 22 8%
Other 48 17%
Unknown 84 29%
Readers by discipline Count As %
Medicine and Dentistry 108 37%
Nursing and Health Professions 31 11%
Immunology and Microbiology 10 3%
Agricultural and Biological Sciences 8 3%
Biochemistry, Genetics and Molecular Biology 7 2%
Other 32 11%
Unknown 94 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 50. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 January 2023.
All research outputs
of 25,386,051 outputs
Outputs from Cochrane database of systematic reviews
of 12,552 outputs
Outputs of similar age
of 278,759 outputs
Outputs of similar age from Cochrane database of systematic reviews
of 227 outputs
Altmetric has tracked 25,386,051 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,552 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 37.0. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,759 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 227 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.