@NeomiShah @HarneetWalia1 @IcahnMountSinai This is what using the AHI did for the determination of the safety of opioids in even "severe" OSA patients. Fake AHI measurement renders CPAP impotent by AHRQ and a false sense of security relevant opioids by @
@neumanmd Hmm "Trust RCTs". Not so fast Dr. It's not that simple "Upon examining the current data, we conclude that opiates/opioids, sedatives and hypnotics examined in this review have no deleterious effect on the severity of OSA..." https://t.co/vE7sW
I missed this tweet, and I regret it. Thank you @CochraneLibrary I will proceed as you request.
@RWJE_BA @hemanth_kanak @elmir1omerovic @drjohnm @kaulcsmc @GreggWStone @f2harrell @yudapearl Here @cochranecollab 14 RCT effects of 10 sedatives or opioids in 293 people with OSA "None of the drugs in this review produced a significant increase in AHI o
@PatientStormDoc @EuroRespSoc @SchizaSophia @cochranecollab @CochraneUK We welcome comments on specific reviews, please see here https://t.co/INZRaZ0Hdu For this review, you can submit your comment/concerns at https://t.co/sJ17QKvttg so that it may go thr
@EuroRespSoc @SchizaSophia @cochranecollab Sry heres link to @CochraneLibrary or possible @CochraneUK review showing misleading conclusion that Opioids & sedatives do not increase severity of OSA (they used the AHI). Recall or at least a update comm
However, there are consequences Here in @cochranecollab review, AHI is the severity measure to show that Opioids & sedatives are safe in patents with obstructive sleep apnea We all agree AHI is not valid severity measure so this paper should be recal
@MichaelESmith @ConserveChange @consiliumsci @cochranecollab A dangerous result of #PathologicalConsensus. @cochranecollab falsely concludes that opiates do not increase severity of #ObstructiveSleepApnea. Many will conclude that it is safe to give them.
A sleep apnea review by @cochranecollab and performed within dogma of 1980s guessed measurements and #PathologicalConsensus. Results are meaningless because the AHI is a guessed measurement. Can't blame them. They didn't know. But now they do. https:/
コクランレビューから、睡眠時無呼吸症への睡眠薬、オピオイドなどの使用について。ゾルピデムやトリアゾラム、レミフェンタニルは夜間SpO2を下げるけど、エスゾピクロンはむしろ重症度を下げると。Zドラッグで差が…一体何が(@[email protected]) http://t.co/druxYiR84t
Effects of opioid, hypnotic & sedating .. on sleep-disrderd breathing in adults ..obstr sleep apnoea #papworthauthors http://t.co/m4t4pgIixQ
Ni opioides, ni hipnóticos ni medicación sedante mejora la respiración durante el sueño en apnea obstructiva http://t.co/MDof6zPZci
New #Cochrane Review: Effects of opioid, hypnotic&sedating meds on sleep-disordered breathing in adults with OSA http://t.co/ENuu0YJLHx
Opioids, hypnotics & sedatives, effects on sleep-disordered breathing in adults w/ obstructive sleep apnoea #Cochrane http://t.co/1KR1UenWmQ
Opioids, hypnotics & sedatives, effects on sleep-disordered breathing in adults w/ obstructive sleep apnoea #Cochrane http://t.co/1KR1UenWmQ
New #Cochrane Review: Effects of opioid, hypnotic&sedating meds on sleep-disordered breathing in adults with OSA http://t.co/ENuu0YJLHx
New #Cochrane Review: Effects of opioid, hypnotic&sedating meds on sleep-disordered breathing in adults with OSA http://t.co/ENuu0YJLHx
Effects of opioid, hypnotic and sedating medications on sleep-disordered breathing in adults with obstructive slee… http://t.co/oeuK0jN7wW
New #Cochrane Review: Effects of opioid, hypnotic&sedating meds on sleep-disordered breathing in adults with OSA http://t.co/ENuu0YJLHx
New #Cochrane Review: Effects of opioid, hypnotic&sedating meds on sleep-disordered breathing in adults with OSA http://t.co/ENuu0YJLHx
No evidence suggests that drugs assessed have deleterious effect on severity of OSA as measured by change in AHI/ODI http://t.co/1nfiJ4O2Ac
14 small trials (N=293) on 10 different drugs. Most trials 1-3 night's duration. Most had mild-moderate OSA http://t.co/ik8qqA67G5
New #Cochrane Review: Effects of opioid, hypnotic&sedating meds on sleep-disordered breathing in adults with OSA http://t.co/ENuu0YJLHx