Prolonged antibiotics for non‐cystic fibrosis bronchiectasis in children and adults

Overview of attention for article published in Cochrane database of systematic reviews, August 2015

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High Attention Score compared to outputs of the same age (93rd percentile)
Good Attention Score compared to outputs of the same age and source (75th percentile)

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Diarrhoea was commonly reported as an adverse event, particularly with an oral intervention. http://ow.ly/QZPbu

No significant difference in hospitalizations OR 0.40, 95% CI 0.14 to 1.11; P value = 0.08 ow.ly/QZNva

271 exacerbations per 1000 people on ABx (95%CI 126 to 385) vs 546 per 1000 in control group. Moderate qual evidence ow.ly/QZNva

18 RCTs on 1157 participants. Antibiotics given for 4to 83 weeks. Limited meta-analysis due to diversity of outcomes ow.ly/QZNva

Double the number of studies (18) in #Cochrane review update: prolonged antibiotics for #bronchiectasis http://ow.ly/QZN1a