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Cochrane Database of Systematic Reviews

Antibiotics for syphilis diagnosed during pregnancy

Overview of attention for article published in Cochrane database of systematic reviews, July 2001
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

policy
1 policy source
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
68 Dimensions

Readers on

mendeley
198 Mendeley
citeulike
1 CiteULike
Title
Antibiotics for syphilis diagnosed during pregnancy
Published in
Cochrane database of systematic reviews, July 2001
DOI 10.1002/14651858.cd001143
Pubmed ID
Authors

Godfrey JA Walker

Abstract

Congenital syphilis is an increasing problem in many developing countries and in the transitional economies of Eastern Europe and the former Soviet Union. In several countries this increase has been aggravated by HIV/AIDS. While the effectiveness of penicillin in the treatment of syphilis in pregnant women and the prevention of congenital syphilis was established shortly after the introduction of penicillin in the 1940s, there is uncertainty about the optimal treatment regimens. To identify the most effective antibiotic treatment regimen (in terms of dose, length of course and mode of administration) of syphilis with and without concomitant infection with HIV for pregnant women infected with syphilis. MEDLINE 1966 to March 2000; EMBASE 1974 to March 2000, the Cochrane Controlled Trials Register (last searched March 2001), the Cochrane Pregnancy and Childbirth group trials register (last searched March 2001) and the references of traditional reviews were searched. Experts in specialist units were contacted. It was planned that any trial in which an attempt is made to allocate treatment for syphilis during pregnancy by a random or quasi-random method would be included in this review. Information was extracted using a data extraction sheet and this included entry criteria, the source of controls, and whether the authors stratified by the stage of pregnancy when the diagnosis of syphilis was made. Twenty six studies met the criteria for detailed scrutiny. However, none of these met the pre-determined criteria for comparative groups and none included comparisons between randomly allocated groups of pregnant women. While there is no doubt that penicillin is effective in the treatment of syphilis in pregnancy and the prevention of congenital syphilis, uncertainty remains about what are the optimal treatment regimens. Further studies are needed to evaluate treatment failure cases with currently recommended regimens and this should include an assessment of the role of HIV infection in cases of prenatal syphilis treatment failure. The effectiveness of various antibiotic regimens for the treatment of primary and secondary syphilis in pregnant women need to be assessed using randomised controlled trials which compare them with existing recommendations.

Mendeley readers

The data shown below were compiled from readership statistics for 198 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
France 1 <1%
Ireland 1 <1%
Unknown 195 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 31 16%
Student > Master 31 16%
Researcher 23 12%
Other 19 10%
Student > Ph. D. Student 16 8%
Other 33 17%
Unknown 45 23%
Readers by discipline Count As %
Medicine and Dentistry 75 38%
Nursing and Health Professions 22 11%
Social Sciences 12 6%
Agricultural and Biological Sciences 8 4%
Psychology 5 3%
Other 26 13%
Unknown 50 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2021.
All research outputs
#3,862,087
of 19,102,798 outputs
Outputs from Cochrane database of systematic reviews
#6,474
of 11,926 outputs
Outputs of similar age
#58,375
of 263,373 outputs
Outputs of similar age from Cochrane database of systematic reviews
#184
of 263 outputs
Altmetric has tracked 19,102,798 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,926 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.0. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,373 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 263 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.