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Cochrane Database of Systematic Reviews

Cholinesterase inhibitors for Alzheimer's disease

Overview of attention for article published in this source, January 2006
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Mentioned by

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2 news outlets
blogs
5 blogs
twitter
42 tweeters
patent
3 patents
peer_reviews
1 peer review site
wikipedia
10 Wikipedia pages

Citations

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1305 Dimensions

Readers on

mendeley
873 Mendeley
citeulike
1 CiteULike
Title
Cholinesterase inhibitors for Alzheimer's disease
Published by
John Wiley & Sons, Ltd, January 2006
DOI 10.1002/14651858.cd005593
Pubmed ID
Authors

Birks, Jacqueline S

Abstract

Since the introduction of the first cholinesterase inhibitor (ChEI) in 1997, most clinicians and probably most patients would consider the cholinergic drugs, donepezil, galantamine and rivastigmine, to be the first line pharmacotherapy for mild to moderate Alzheimer's disease.The drugs have slightly different pharmacological properties, but they all work by inhibiting the breakdown of acetylcholine, an important neurotransmitter associated with memory, by blocking the enzyme acetylcholinesterase. The most that these drugs could achieve is to modify the manifestations of Alzheimer's disease. Cochrane reviews of each ChEI for Alzheimer's disease have been completed (Birks 2005, Birks 2005b and Loy 2005). Despite the evidence from the clinical studies and the intervening clinical experience the debate on whether ChEIs are effective continues.

Twitter Demographics

The data shown below were collected from the profiles of 42 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 873 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 9 1%
United States 6 <1%
Netherlands 2 <1%
Italy 2 <1%
Ireland 2 <1%
Brazil 1 <1%
Pakistan 1 <1%
Sweden 1 <1%
Switzerland 1 <1%
Other 5 <1%
Unknown 843 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 164 19%
Student > Ph. D. Student 132 15%
Student > Master 122 14%
Researcher 112 13%
Student > Doctoral Student 50 6%
Other 165 19%
Unknown 128 15%
Readers by discipline Count As %
Medicine and Dentistry 226 26%
Agricultural and Biological Sciences 98 11%
Neuroscience 76 9%
Psychology 57 7%
Pharmacology, Toxicology and Pharmaceutical Science 53 6%
Other 198 23%
Unknown 165 19%