@sheacolonics @tednaiman “When we subgrouped according to replacement for SFA, the PUFA replacement group suggested a 21% reduction in cardiovascular events” https://t.co/nrM0hqWpGH
So, what happens when you reduce dietary satuated fat? A Cochrane review found cutting down on saturated fat led to a 17% reduction in the risk of cardiovascular disease (including heart disease and strokes. https://t.co/LwEAhChwsz
Hooper, L., Martin, N., Jimoh, O. F., Kirk, C., Foster, E., & Abdelhamid, A. S. (2020). Reduction in saturated fat intake for cardiovascular disease. Cochrane database of systematic reviews, (8). https://t.co/8cEYQfc48n (6/8)
@TamarHaspel https://t.co/mNl98pflJL SR of RCTs: "We found little or no effect of reducing saturated fat on all‐cause mortality" https://t.co/Ec925X8txL Statin benefits could be from their anti-inflammatory effects. Statin evidence may not be relevant to t
@SBakerMD @drdairy50 These correlations are not good evidence re saturated fats. Stronger evidence: Cochrane review of randomized controlled trials: replacing saturated fat with unsaturated fat reduces the risk of CVD events, esp when blood cholesterol wa
@ElizabethLePla @zoeharcombe @BenBikmanPhD @bigfatsurprise Sure! Here you go: https://t.co/nrM0hqWpGH
RT @KetoCounselor: Reduction in saturated fat intake for cardiovascular disease. Cochrane database of systematic reviews, (8). (4/6) https…
RT @KetoCounselor: Reduction in saturated fat intake for cardiovascular disease. Cochrane database of systematic reviews, (8). (4/6) https…
Reduction in saturated fat intake for cardiovascular disease. Cochrane database of systematic reviews, (8). (4/6) https://t.co/8cEYQfbwiP
@vapidbobcat @danyal9600 @BioLayne You haven’t actually posted where this study comes from once. That said we have a larger mega analysis with more RCTs showing that “reducing dietary saturated fat reduced the risk of combined cardiovascular events by 17%”
@DietHeartNews @Edward_Smith92 I agree that we're not lab rats. But human studies have altered diary/meat OR sat fat of diets (typical, mixed meals). Sat fat has a clear impact on circulating cholesterol - that doesn't mean "don't eat any foods with sat
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
@StephenPiment @Meaningness Good RCTs, that randomize people to different diets and examine the effects on hard clinical outcomes such as cardiovascular events or mortality, (1) are possible and (2) exist. For example, see this Cochrane review of RCTs ab
@lumpenspace For context, meta-analyses looking at CV events instead of biomarkers tend to be consistent with this MA. PUFAs may reduce the risk of CV events when compared to SFAs. (Though the effect of MUFAs is unclear and there’s no difference found for
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
@DBelardoMD @AviBittMD RCTs: "We found little or no effect of reducing saturated fat on all‐cause mortality or CVD mortality" https://t.co/mNl98peNUd It's too bad there's no convincing evidence that reducing saturated fat saves lives. It would be nice to
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
RT @Rizzenhouse: These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
These people, man. “Sure” 🤓 https://t.co/Xos1QvKE5G
@gildone84 @Graham_Drew @ggkuhnle @drgarethroberts @maurice_1960 A) the MCE gave the intervention group trans fats. B) The Ramsden meta is not as comprehensive as the more recent Cochrane review. Ramsden’s methodology is absolutely wild. See: https://t.co
@renatodumbra @MacroFour @LDLSkeptic If SFA ⬆️ LDL and LDL causes CVD, it does not follow SFA cause CVD - https://t.co/7nXIMchqd6 LDL per se harmless - https://t.co/eCD7XFPi8s See our comments to Cochrane - https://t.co/5C8zYOQtLm And further analysis u
@MacroFour @ZahcM @LDLSkeptic 2 great papers for you: https://t.co/Si3toLXMMl https://t.co/rLPLItApnE
@carnivore_jt This one is better. It looked at RCTs it also took into account the threshold issue https://t.co/4xENk8aWDM
@ketogrillbakery Hooper 2020 was the Cochrane review meta-analysis for RCTs on saturated fat reduction. The Minnesota Coronary Experiment was excluded because the average duration was too short (the inclusion criteria called for 24 months or more) https:/
@ESYudkowsky Bad take. Keys was not a scientific fraud: https://t.co/P7Cc1HFPlF But who cares anyways? We have much better evidence now that shows that replacing SFA with PUFA (e.g., veg oils) reduces cardiovascular disease. https://t.co/qjqgVE6aA4
@ESYudkowsky Is that actually true? Cochrane did a meta-analysis of fifteen more recent RCTs, and found that the effect of saturated fat on health was either neutral or bad, definitely not positive as the thread claims https://t.co/4uceVyEuEw
Cochrane-katsauksessa havaittiin riskisuhde 0.94 (95% luottamusväli 0.78-1.13, näytön varmuus oli kohtalainen) sydän- ja verisuonitautikuolleisuuden osalta. "Reducing saturated fat intake probably makes little or no difference to cardiovascular mortality."
@Kirsten3531 Random nutrition podcasts aren’t the best source of nutrition information. > The included long‐term trials suggested that reducing dietary saturated fat reduced the risk of combined cardiovascular events by 17% [RR 0.83, 95% CI 0.70 to 0.9
@drewcifer513 @TijuJohn8 @syedsalman97 @PicturesFoIder Here’s a meta-analysis of randomised controlled trials that looked at this question, and found replacing saturated fat with PUFA reduces CVD incidence by 17%: https://t.co/nrM0hqWXwf
@exfatloss @FrogHarmless @Tellit007 “The included long‐term trials suggested that reducing dietary saturated fat reduced the risk of combined cardiovascular events by 17% (risk ratio (RR) 0.83; 95% confidence interval (CI) 0.70 to 0.98 […])” https://t.co/
@Lateralthinka75 @ChrisPalmerMD I don’t think fat in and of itself is harmful. I believe if you consume a eucaloric diet, MUFA and PUFA are healthful. Saturated fat from, say, animal flesh though? I would say there’s overwhelming evidence that increases in
@Benuovir @ArkhamFantasy @ChrisPalmerMD That’s fair. I highly recommend looking at the following meta-analysis on this question. https://t.co/nrM0hqWpGH
@BenDavi13814607 @MohammedAlo Multiple meta-analyses of RCTs and genetic studies find a log-linear relationship between lower LDL-c and lower CVD, and reductions in saturated fat and lower CVD too. https://t.co/zV81852dnB https://t.co/rTtlii1T6d http
🍗🌭🍔🍟🍕Kesan mengurangkan lemak tepu yang dimakan terhadap risiko penyakit jantung 🫀🧠 Klik sini untuk info tambahan 👇🏼 https://t.co/5Jl0XYwfd1 #cochrane #cochranemalaysia #cochraneevidence #cochranelibrary #cochraneorg #cochranelibrary #lemaktepu #penyaki
@CarnivoreIs @BHBEnjoyer @EarthlingAus The subgroup analysis here clearly shows CVD incidence rises as the 10%e threshold is crossed: https://t.co/Rfr98LOve3
@CarnivoreIs @BHBEnjoyer @EarthlingAus No, the best meta-analysis on the subject looked at SFA intake and CVD events: https://t.co/nrM0hqWpGH
@CarnivoreIs @BHBEnjoyer @EarthlingAus We have robust evidence that SFA intake above 10%e increases incidence of CVD: https://t.co/nrM0hqWpGH
@AaronBergman18 @ChadNotChud “When we subgrouped according to replacement for SFA, the PUFA replacement group suggested a 21% reduction in cardiovascular events” https://t.co/lROAKiCTzm
@jmmulet Llevo días pensando en esto. He mirado esto https://t.co/MNoNofBPPr y no me ha impresionado mucho. Hay otros aspectos de la salud relacionados con las grasas saturadas aparte de la salud cardiovascular? A lo mejor estoy buscando mal.
@Paul_James_1 @shelly_187 I linked it purely to explain the chart, it doesn't matter who he is really. I linked it to explain why there is conflicting information out there. https://t.co/w3yon9Ey4B
Hyvä esimerkki minkä takia keinotekoiset raja-arvot ovat ongelmallisia. Mitä satunnaistettu tutkimusnäyttö kertoo tyydyttyneiden rasvojen vähentämisen hyödyistä? https://t.co/ZskScydbLZ
@aCarnivoreDiet @BioLayne "The included long‐term trials suggested that reducing dietary saturated fat reduced the risk of combined cardiovascular events by 17%" https://t.co/Si3toLXMMl
@trigsjourney https://t.co/1UCivsx0VY 56,675 participants The included long‐term trials suggested that reducing dietary saturated fat reduced the risk of combined cardiovascular events by 17%
@cashandcarrots @SentientBlobBob @CaryKelly11 It doesn't matter. The data today is clear that Ancel Keys was right about saturated fat: https://t.co/4xENk8aWDM
@b2hcraig Or just the advance of science 🤷 https://t.co/4zogcmQbM1
@aCarnivoreDiet @BioLayne “The included long-term trials suggested that reducing dietary saturated fat reduced the risk of combined cardiovascular events by 17%” https://t.co/3LKn3xCX1A
RT @ZahcM: They continue to include a study with many red flags and "concerns of fraud." As we noted 👇 https://t.co/uFrWirh2Ed https://t…
@carniyogi @SteAssent Zero? By reducing your LDL-c levels, you can even lower the risk of cardiovascular events. Here's a systematic review w meta-analysis on Cochrane: https://t.co/RSoomf6E06
RT @ZahcM: They continue to include a study with many red flags and "concerns of fraud." As we noted 👇 https://t.co/uFrWirh2Ed https://t…
RT @ZahcM: They continue to include a study with many red flags and "concerns of fraud." As we noted 👇 https://t.co/uFrWirh2Ed https://t…
They continue to include a study with many red flags and "concerns of fraud." As we noted 👇 https://t.co/uFrWirh2Ed https://t.co/jxm3neoIxe
@rootkits10056 @ChadNotChud Yeah he is basically telling us he failed 1st grade math without telling us he failed 1st grade math. Supposedly reduces deaths from CHD yet does not reduce total all cause mortality. Hmmm so 2 - 1 = 2! https://t.co/pIhCmzyd8X
@DavidVio2 E.g. https://t.co/RmcUnhtXfl Replacing saturated fat with polyunsaturated fat reduced risk of CVD events (though statistical significance was not reached for overall mortality)
@lcmail2 @Ainz__Sama @rc_tullius @vegan_logic Saturated fats have been demonstrated over and over to increase risk of CVD. RCTs that actually have sufficient power and aren't confounded by trans fats show this. https://t.co/4xENk8aWDM
Reduction in saturated fat intake for cardiovascular disease https://t.co/lxeZKcSNDk Cochrane warning https://t.co/Dhnksb72ME
@robertlufkinmd Better quality studies disagree: https://t.co/MxyXqMoNDi
@Gerlat_Of_Rivia @malott_austin @hum_dunkin https://t.co/elNNJ4VqFQ https://t.co/SCMFUKpzrQ low and high density lipoprotein are acutely associated with chronic heart disease. These enter the body through saturated fats, like butter and tropical oils, and
@bigfatsurprise Or this one? https://t.co/NC8Taj3b7H There are more, but for you to be so confident in your assertions just demonstrates YOUR clear lack of objectivity
@primary3down "reducing dietary saturated fat reduced the risk of combined cardiovascular events by 17%" "greater reductions in saturated fat (reflected in greater reductions in serum cholesterol) resulted in greater reductions in risk of CVD events" http
ودي الدراسات الحديثة https://t.co/Zr6ALny7yT أيوة في دراسات اتعلمت بتقول أن مفيش فرق ف استخدام الدهون المشبعة عن الدهون التانية لكن لسة الevidence مش بالقوة اللي تغير guidelines أنا مش باخد المواضيع شخصيا أنا طبيبة وأكاديمية وحفضل احترم التوصيات والبحث ا
@Malnutridos El meta de Hooper analiza SFA en general, y su sustitución por otros macronutrientes. https://t.co/AKVNAEMjwf
@MyNutritionSci right but which month. from the screen grab I think its the previous version before they added Sydney and the numbers changed? https://t.co/zPCKMsyJGy
Replacing the energy from saturated fat with polyunsaturated fat or complex carbohydrate appear to be useful strategies to reduce risks of cardiovascular events. https://t.co/Xa6ymtBOAa
@gAlecsyBrain @dr_cois @TheBhupiThakur @NutritionMadeS3 @raulmartin_n “15 RCTs, that used a variety of interventions from providing all food to advice on reducing saturated fat” “reducing dietary saturated fat reduced the risk of combined cardiovascular e
@MohammedAlo There is a slightly later version (21st Aug 2020 vs 19 May 2020) of the Cochrane review at Doi:10.1002/14651858.CD011737.pub3 https://t.co/rbEfHlrr7s
@ExMuslimsMN No there is a basically a consensus. All (except two badly made ones) RCTs show that saturated fat increases risk. This is the biggest meta analysis on the topic: https://t.co/4xENk8aWDM
@me_fafo @RomeoStevens76 @bananamelter @lillybilly299 @sunofdopamine @romeostevens Myth? Really? You mean the myth that's been shown by almost every single RCT out there? That myth? https://t.co/4xENk8aWDM
Reduction in saturated fat intake for cardiovascular disease https://t.co/iwP2Zu1N34 Cochrane warning
@PeterFaberSP @NutritionMadeS3 15 RCTs. “The included long‐term trials suggested that reducing dietary saturated fat reduced the risk of combined cardiovascular events by 17% (risk ratio (RR) 0.83; 95% confidence interval (CI) 0.70 to 0.98” Looks like he
Wirkung der eingeschränkten Aufnahme gesättigter Fettsäuren über die Nahrung auf das Risiko von Herzerkrankungen https://t.co/2kz1IyfY88
@SteveLome Just one little problem...what you're saying is not borne out by the evidence. Saturated fat does not cause cause heart disease. https://t.co/jr4eolJmV8 https://t.co/3TpNBtK4N5
@TyRBeal Saturated fat? How did that get on this list? Did you just ignore the Cochrane review? https://t.co/jr4eolJmV8 https://t.co/stKvDZ6BV1
@MasalaFry69 Largest meta analysis ever done on randomized control trials: https://t.co/6gaBww9D0N
@MasalaFry69 @JimmySm58405905 @JaicSam @kevinnbass It all comes down to dose. We know from the largest analysis ever done on randomized controlled trials that the effect of saturated fat on cardiovascular disease is shaped like an S: https://t.co/6gaBww9
@CarnivoreIs @JustinBosley12 @andyswarbs @bclj199 @EL0N__TUSK @WeirdConfidence @VeganRecovering @Snoreflake @RickTheV1 @sciencebyjae Maybe he should check his hierarchy of evidence 😉 and check out the 5 meta analyses that found no significant associations
@cck197 @realDaveFeldman A small effect size on a disease that kills millions every year can save thousands of lives, don't you think? See: https://t.co/3LKn3xCX1A
@CaryKelly11 1. This is a 'Reassessment and Proposal', not a study. 2. The paper does not list any conflicts of interest. (Biased) 3. Cohort studies they reference from "...questionnaires to assess diet" is weak research. Study: https://t.co/v8Lljeg14J S
@OurLack Nina's article is the stupidest thing. What is wrong with you? She didn't even read the Cochrane study. Read the author's conclusions yourself. Nina cherry-picked quotes about specific events they weren't sure about. Complete dishonesty. https://
@ifbacongrewont1 @sciencebyjae Is this inaccurate? Why? https://t.co/nb5Li61oOv
@TheBrainBattery I think it's well understood that more SFA increase CVD rates. A Cochrane meta analysis of randomized controlled trials showed reduced CVD rate with a reduction of SFA. They also showed a reduction in LDL-C, which could extend lifespan in
@bigfatsurprise @nntaleb @LuisCLCorreia @DrDamluji @cochranecollab @nationallipid Correct. @DrDamluji cited Cochrane (Hooper 2020). Nina then mentioned Cochrane was one of the articles she covered in her review. Taleb then claimed Nina presented Hooper 202
"Reducing saturated fat intake for at least two years causes a potentially important reduction in combined cardiovascular events. Replacing the energy from saturated fat with polyunsaturated fat or carbohydrate appear to be useful strategies" https://t.co
RT @drmikehart: @nntaleb @bigfatsurprise Cochrane review of 15 randomized controlled trials: "reducing saturated fat intake for at least…